Exosomes ASCE+ at Nowa Estetyka Wrocław

Exosomes ASCE+ offer an effective method for skin regeneration, wrinkle reduction, and improving overall skin appearance. Exosomes provide the skin with many substances that aid in regeneration and renewal, stimulating the production of collagen and elastin, which helps improve the skin’s elasticity and firmness. The growth factors and cytokines they contain stimulate tissue regeneration and enhance skin condition. Exosome treatments also help reduce hyperpigmentation and scarring.

What are exosomes and what is their function?

Exosomes, produced by stem cells and mesenchymal cells (MSC), contain various substances such as proteins, growth factors, cytokines, and elastin, which are vital for the skin’s health and appearance.

Exosomes are much smaller than cells—typically ranging in diameter from 30 to 150 nanometers. In comparison, most cells measure between 10 to 30 micrometers, making exosomes about 1000 times smaller. This allows them to easily penetrate various anatomical barriers, such as the cell membrane, reaching deeper layers of the skin for regeneration.

The growth factors and cytokines present in exosomes have the ability to stimulate cell proliferation. They promote collagen and elastin production and stimulate angiogenesis processes, which involve the formation of new blood vessels.

Indications for ASCE+ exosome treatment

  • Skin requiring regeneration and hydration
  • Wrinkles and fine lines
  • Scarring
  • Skin discoloration and pigmentation spots
  • Skin irregularities
  • Calming of inflammatory conditions (atopy, psoriasis, hypermelanosis)
  • Acne relief

How is the exosome treatment performed?

The procedure involves applying ASCE+ exosomes, obtained using the patented ExoSCRTTM ™ technology from damask rose stem cells, which closely resemble human exosomes. A physician administers the exosomes to damaged skin using techniques such as microneedling.

Preparation for the procedure

No special preparation is required from the patient for exosome treatment. During the consultation, it is essential to inform the doctor about any medications being taken and previous aesthetic treatments on the same skin area, especially if more procedures are planned. This will help in creating an appropriate treatment plan so that future treatments do not negate the achieved results.

Before administering the exosomes, makeup must be removed, and the skin disinfected in the treated area. The procedure is short and not painful.

Aftercare and post-treatment care

The procedure does not leave visible needle marks; however, the skin may remain slightly red for a few hours after the treatment, which is a typical reaction.

The skin heals quickly, and patients can return to their daily activities and skincare routine immediately. After the procedure, it is recommended to limit UV exposure and use high SPF creams.

Exosome treatment results

  • Improved skin elasticity and hydration
  • Reduction of wrinkles and fine lines
  • Scar reduction (when combined with ablative laser)
  • Smoothing of uneven skin texture
  • Improved and even skin tone, reduction of discoloration and pigmentation spots
  • Reduction of inflammation
  • Increased effectiveness of other aesthetic treatments

When will I see the first results?

The time needed to achieve visible results can vary depending on factors like the general condition of the skin, the patient’s health, and the severity of the damage being addressed. Typically, exosome treatment results on the face, neck, or décolletage become visible within 2-3 days. In cases of very deep wrinkles, exosome treatment alone may not yield satisfactory results, and a combined therapy (e.g., exosomes plus fractional laser therapy) may be necessary.

How many treatments are needed to achieve optimal results?

Exosome treatments for the face or décolletage are typically performed in series: 2-6 treatments spaced about 2 weeks apart. The number of treatments will depend on the individual needs of the patient and the extent of skin damage.

Exosomes can also be used as a complementary treatment after procedures like ablative laser therapy, platelet-rich plasma, and platelet-rich fibrin. When used alongside other aesthetic treatments, exosomes accelerate skin regeneration and reduce recovery time (which, after fractional laser therapy, is about 7 days). In this case, a single treatment may suffice.

How long do the treatment results last?

The duration of results after the first series of treatments will depend on the patient’s age, lifestyle, diet, regular skincare, and overall health. However, the results are typically temporary, and to maintain the effects, the treatment must be repeated.

A maintenance series can be repeated after about 6-12 months, depending on individual needs.

Is the treatment safe?

ASCE+ exosomes are hypoimmunogenic and very rarely trigger an immune response in the body. Exosomes are not living cells and do not have cellular memory, making them safe for human use.

Contraindications for exosome treatment

Exosome administration is safe and generally does not cause allergies or severe side effects. However, there are a few contraindications, such as:

  • Pregnancy and breastfeeding – due to the lack of studies on the safety of exosome use during this period
  • Autoimmune diseases such as lupus, rheumatoid arthritis, or systemic sclerosis (the therapy may affect the immune system and increase the risk of complications)
  • Anticoagulant therapy – exosomes may influence blood clotting, so consultation with a primary physician is recommended

Potential side effects and risks associated with the treatment

Possible side effects of exosome administration include:

  • Allergic reactions – although rare, exosomes can cause an autoimmune reaction. Possible allergy symptoms include redness, itching, swelling, burning, and rash.
  • Cosmetic imperfections – in some cases, undesirable skin changes such as redness or pimples may occur after the treatment.
  • Pigmentation spots – exosomes may help treat skin pigmentation disorders, but some patients may experience new pigment spots or worsening of existing ones. This is a rare side effect but can happen, especially in patients with sensitive skin.
  • Infections – if proper care is not taken of the injection sites.